4 treatments each, using Lipocollect 200 and Lipocollect 550 in the same patient

(calculated plasmavolume of the patient: 2950 ml)

Lipocollect 200 (Each adsorber was loaded four times in one session.)

The perfused plasma volume in one session was about 5000 ml, duration of apheresis 2-3 h, instruments: Cobe Spectra + Adasorb.

Date	15.04. 2004		04.05.2004		11.05.2004		01.06.2004		mean
time of taking samples	pre	post	pre	post	pre	post	pre	post	pre	post	% of pre	%red
Cholesterol (mg/dl)	293	115	247	109	225	96	244	99	252	105	42	58
LDL-Chol. (mg/dl) (% of initial value)	189	61 (32,3)	162	53 (32,7)	148	45 (30,4)	159	49 (30,8)	165	52	31.5	68,5
HDL-Chol. (mg/dl)	64	40	59	51	55	44	53	38	58	43	75	25
Triglycer. (mg/dl)	131	48	129	45	109	38	93	36	115	42	36	64
Total protein (g/l )	71,9	55,4	67,6	56,9	64,7	52,7	66,5	53,0	67,7	54,5	80,5	19,5
Albumin (g/l )	-	-	41,7	37,9	39,1	34,5	40,0	34,0	40,3	35,5	88,1	11,9
Fibrinogen (mg/dl)	-	-	-	-	-	-	-	-

Lipocollect 550 (Each adsorber was loaded once only during a session.)

The perfused plasma volume in one session was about 6000 ml, duration of apheresis 2-3 h, instrument: Cobe Spectra, without ADAsorb.

Date	28.02.2005		05.03.2005		12.03.2005		20.03.2005		mean
time of taking samples	pre	post	pre	post	pre	post	pre	post	pre	post	% of pre	%red
Cholesterol (mg/dl)	200*	88	232	95	261	104	230	95	231	96	41,6	58,4
LDL-Chol. (mg/dl) (% of initial value)	134	39 (29,1)	161	44 (27,3)	158	45 (28,5)	148	38 (25,7)	150	42	28	72
HDL-Chol. (mg/dl)	53	46	58	49	68	57	58	51	59	51	86	14
Triglycer. (mg/dl)	157	83	131	64	103	73	202	59	148	70	47	53
Total protein (g/l )	67,2	56,8	67,7	59,8	71,5	61,8	66,8	57,0	68,3	58,9	86,2	13,8
Albumin (g/l )	42,0	38,0	42,0	37,6	47,0	40,2	41,6	36,6	43,2	38,1	88,2	11,8
Fibrinogen (mg/dl)	298	256	287	266	285	241	263	237	283	250	88,3	11,7